6-broMo-2,4-difluoro-3-(triMethylsilyl)benzaldehyde
98%
science Other reagents with same CAS 651326-71-5
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description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of kinase inhibitors and other bioactive molecules. Its aldehyde functionality allows for easy derivatization, enabling the formation of imines, alcohols, or extended aromatic systems through cross-coupling reactions. The trimethylsilyl group acts as a protective handle and can be selectively removed or transformed, offering flexibility in synthetic routes. The presence of bromo and fluoro substituents provides sites for palladium-catalyzed coupling reactions, making it valuable in medicinal chemistry for building complex aromatic frameworks. Commonly employed in research settings for the preparation of fluorinated drug candidates with improved metabolic stability and binding affinity.
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