2-(METHYLTHIO)PYRIMIDINE-5-BORONIC ACID PINACOL ESTER
98%
science Other reagents with same CAS 940284-18-4
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description Product Description
Used as a key intermediate in pharmaceutical synthesis, particularly in Suzuki-Miyaura cross-coupling reactions to construct biaryl systems found in active pharmaceutical ingredients. Its boronic ester group enables efficient carbon-carbon bond formation under mild conditions, making it valuable in drug discovery for developing kinase inhibitors and other heterocyclic compounds. The methylthio group can act as a directing group or be further modified to thioether, sulfoxide, or sulfone functionalities, adding versatility in late-stage functionalization. Commonly employed in the development of agrochemicals and medicinal chemistry research due to its stability and reactivity profile.
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