N-(2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide

95%

Reagent Code: #214782
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CAS Number 139554-72-6

science Other reagents with same CAS 139554-72-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 366.44 g/mol
Formula C₁₆H₂₂N₄O₄S
badge Registry Numbers
MDL Number MFCD02094223
thermostat Physical Properties
Melting Point 123-129 °C
Boiling Point 743.5±55.0 °C(Predicted)
inventory_2 Storage & Handling
Storage -20°C, Inert Gas

description Product Description

Used as a linker in antibody-drug conjugates (ADCs), enabling targeted delivery of cytotoxic agents to cancer cells. Its structure allows stable attachment between the antibody and the drug payload, improving pharmacokinetics and reducing off-target effects. The compound’s functional groups support conjugation chemistry, particularly through maleimide-thiol coupling, commonly used in bioconjugation. It helps maintain the integrity of the ADC in circulation while allowing efficient drug release inside the target cell.

Available Sizes & Pricing

Size Availability Unit Price Quantity
1mg
10-20 days ฿2,720.00
5mg
10-20 days ฿6,790.00
10mg
10-20 days ฿10,160.00
25mg
10-20 days ฿20,360.00
100mg
10-20 days ฿48,800.00
250mg
10-20 days ฿73,190.00
50mg
10-20 days ฿32,530.00
N-(2-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide
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Used as a linker in antibody-drug conjugates (ADCs), enabling targeted delivery of cytotoxic agents to cancer cells. Its structure allows stable attachment between the antibody and the drug payload, improving pharmacokinetics and reducing off-target effects. The compound’s functional groups support conjugation chemistry, particularly through maleimide-thiol coupling, commonly used in bioconjugation. It helps maintain the integrity of the ADC in circulation while allowing efficient drug release inside the

Used as a linker in antibody-drug conjugates (ADCs), enabling targeted delivery of cytotoxic agents to cancer cells. Its structure allows stable attachment between the antibody and the drug payload, improving pharmacokinetics and reducing off-target effects. The compound’s functional groups support conjugation chemistry, particularly through maleimide-thiol coupling, commonly used in bioconjugation. It helps maintain the integrity of the ADC in circulation while allowing efficient drug release inside the target cell.

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