N-(2-Chloro-4-(trifluoromethyl)phenyl)-2-(2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-(4-(5-hydroxy-6-methylpyrimidine-4-carbonyl)piperazin-1-yl)-7-oxo-[1,2,4]triazolo[1,5-a]pyrimidin-4(7H)-yl)acetamide, sodium salt

95%

Reagent Code: #214916
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CAS Number 2869954-35-6

science Other reagents with same CAS 2869954-35-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 725.07 g/mol
Formula C₃₁H₃₁ClF₃N₉NaO₅
inventory_2 Storage & Handling
Storage 2-8°C, Inert Gas

description Product Description

Used as a potent inhibitor of the JAK1 enzyme (Janus kinase 1), which plays a key role in cytokine signaling pathways involved in inflammation. It is developed for use in treating autoimmune disorders, such as rheumatoid arthritis, psoriasis, and psoriatic arthritis. The JAK1 inhibition helps reduce inflammation, alleviate pain, swelling, and other symptoms arising from immune system dysregulation. It offers advantages in efficacy and safety compared to previous treatments in the same class. The sodium salt form enhances water solubility, improving oral absorption and leading to stable blood levels. Clinical studies are ongoing to evaluate its effectiveness in other chronic inflammatory conditions.

Available Sizes & Pricing

Size Availability Unit Price Quantity
100mg
10-20 days ฿26,790.00
250mg
10-20 days ฿45,530.00
1g
10-20 days ฿122,930.00
N-(2-Chloro-4-(trifluoromethyl)phenyl)-2-(2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-(4-(5-hydroxy-6-methylpyrimidine-4-carbonyl)piperazin-1-yl)-7-oxo-[1,2,4]triazolo[1,5-a]pyrimidin-4(7H)-yl)acetamide, sodium salt
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Used as a potent inhibitor of the JAK1 enzyme (Janus kinase 1), which plays a key role in cytokine signaling pathways involved in inflammation. It is developed for use in treating autoimmune disorders, such as rheumatoid arthritis, psoriasis, and psoriatic arthritis. The JAK1 inhibition helps reduce inflammation, alleviate pain, swelling, and other symptoms arising from immune system dysregulation. It offers advantages in efficacy and safety compared to previous treatments in the same class. The sodium s

Used as a potent inhibitor of the JAK1 enzyme (Janus kinase 1), which plays a key role in cytokine signaling pathways involved in inflammation. It is developed for use in treating autoimmune disorders, such as rheumatoid arthritis, psoriasis, and psoriatic arthritis. The JAK1 inhibition helps reduce inflammation, alleviate pain, swelling, and other symptoms arising from immune system dysregulation. It offers advantages in efficacy and safety compared to previous treatments in the same class. The sodium salt form enhances water solubility, improving oral absorption and leading to stable blood levels. Clinical studies are ongoing to evaluate its effectiveness in other chronic inflammatory conditions.

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