N-(2-Chloro-4-(trifluoromethyl)phenyl)-2-(2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-(4-(5-hydroxy-6-methylpyrimidine-4-carbonyl)piperazin-1-yl)-7-oxo-[1,2,4]triazolo[1,5-a]pyrimidin-4(7H)-yl)acetamide, sodium salt
95%
science Other reagents with same CAS 2869954-35-6
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description Product Description
Used as a potent inhibitor of the JAK1 enzyme (Janus kinase 1), which plays a key role in cytokine signaling pathways involved in inflammation. It is developed for use in treating autoimmune disorders, such as rheumatoid arthritis, psoriasis, and psoriatic arthritis. The JAK1 inhibition helps reduce inflammation, alleviate pain, swelling, and other symptoms arising from immune system dysregulation. It offers advantages in efficacy and safety compared to previous treatments in the same class. The sodium salt form enhances water solubility, improving oral absorption and leading to stable blood levels. Clinical studies are ongoing to evaluate its effectiveness in other chronic inflammatory conditions.
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