Used primarily in dermatological research, this compound has been investigated for its skin-lightening properties due to its ability to inhibit melanin production. It was historically explored in topical formulations aimed at reducing hyperpigmentation, such as melasma and age spots. However, due to concerns over systemic absorption and potential hormonal side effects, its use in cosmetic and therapeutic products has been largely discontinued. Currently, it serves mainly as a reference substance in studies evaluating estrogenic activity in chemical compounds.