N-(4-Methoxybenzyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinamide
≥95%
Reagent
Code: #215566
CAS Number
2828440-26-0
science Other reagents with same CAS 2828440-26-0
blur_circular Chemical Specifications
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Molecular Information
Weight
368.23 g/mol
Formula
C₂₀H₂₅BN₂O₄
thermostat
Physical Properties
Boiling Point
559.7±50.0 °C(Predicted)
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Storage & Handling
Density
1.16±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical synthesis. Its boronate ester group facilitates coupling with aryl halides under palladium catalysis, making it valuable in constructing complex heteroaromatic systems. Commonly applied in the development of bioactive molecules and drug candidates where precise molecular architecture is required. The picolinamide moiety enhances stability and coordination with metal catalysts, improving reaction efficiency. Also employed in medicinal chemistry for late-stage functionalization of drug-like compounds.
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