N-(1-((6aR,8R,9aR)-9-Cyano-9-hydroxy-2,2,4,4-tetraisopropyltetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide
97%
science Other reagents with same CAS 1194441-31-0
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description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly PROTACs (proteolysis-targeting chimeras). Its structural features enable selective binding to specific enzymes or receptors, facilitating the degradation of disease-related proteins. The cyano and hydroxy groups support molecular interactions critical for biological activity, while the rigid polycyclic framework enhances stability and binding specificity. Commonly employed in oncology and neurodegenerative disease drug development due to its ability to modulate protein levels within cells.
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