N-Methyl-4-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenoxy)picolinamide
97%
Reagent
Code: #215746
CAS Number
1285533-84-7
science Other reagents with same CAS 1285533-84-7
blur_circular Chemical Specifications
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Molecular Information
Weight
430.38 g/mol
Formula
C₂₁H₁₇F₃N₄O₃
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Registry Numbers
MDL Number
MFCD29041974
thermostat
Physical Properties
Melting Point
187.6 °C
Boiling Point
498.1±45.0 °C(Predicted)
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Storage & Handling
Density
1.399±0.06 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used in pharmaceutical research as a potent and selective inhibitor of Janus kinase 1 (JAK1), showing potential for treating autoimmune and inflammatory diseases such as rheumatoid arthritis and psoriasis. Its structure enables high selectivity for JAK1 over other JAK family members, which may reduce side effects commonly associated with broader JAK inhibition. Currently investigated in preclinical and clinical studies for optimizing therapeutic efficacy and safety in chronic inflammatory conditions.
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