2-Chloro-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)acetamide

95%

Reagent Code: #215915
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CAS Number 1957235-51-6

science Other reagents with same CAS 1957235-51-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 349.73 g/mol
Formula C₁₅H₁₂ClN₃O₅
badge Registry Numbers
MDL Number MFCD32633381
thermostat Physical Properties
Boiling Point 691.4±55.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.617±0.06 g/cm3(Predicted)
Storage 2-8°C, Sealed, Inert Gas

description Product Description

Used primarily in the synthesis of immunomodulatory and anticancer agents. It serves as a key intermediate in the preparation of targeted protein degraders, particularly cereblon E3 ligase modulators. These compounds are designed to selectively bind and degrade disease-causing proteins, making them valuable in the development of treatments for hematological cancers such as multiple myeloma and myelodysplastic syndromes. Its structure enables conjugation in bifunctional molecules where it links target-binding ligands to E3 ligase recruiters, facilitating ubiquitination and subsequent degradation of specific proteins. Also explored in research settings for optimizing pharmacokinetic properties and selectivity in novel therapeutics.

Available Sizes & Pricing

Size Availability Unit Price Quantity
250mg
10-20 days ฿6,180.00
1g
10-20 days ฿16,650.00
5g
10-20 days ฿63,130.00
2-Chloro-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)acetamide
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Used primarily in the synthesis of immunomodulatory and anticancer agents. It serves as a key intermediate in the preparation of targeted protein degraders, particularly cereblon E3 ligase modulators. These compounds are designed to selectively bind and degrade disease-causing proteins, making them valuable in the development of treatments for hematological cancers such as multiple myeloma and myelodysplastic syndromes. Its structure enables conjugation in bifunctional molecules where it links target-bin

Used primarily in the synthesis of immunomodulatory and anticancer agents. It serves as a key intermediate in the preparation of targeted protein degraders, particularly cereblon E3 ligase modulators. These compounds are designed to selectively bind and degrade disease-causing proteins, making them valuable in the development of treatments for hematological cancers such as multiple myeloma and myelodysplastic syndromes. Its structure enables conjugation in bifunctional molecules where it links target-binding ligands to E3 ligase recruiters, facilitating ubiquitination and subsequent degradation of specific proteins. Also explored in research settings for optimizing pharmacokinetic properties and selectivity in novel therapeutics.

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