N-Trityl-L-alanine diethylammonium salt
95%
science Other reagents with same CAS 80514-65-4
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description Product Description
Used in peptide synthesis as a protected derivative of L-alanine, where the trityl group shields the alpha-amino group to enable selective coupling reactions and prevent unwanted side reactions. The trityl group offers strong steric and electronic protection, stable in basic and neutral conditions but easily removable under mild acidic conditions (e.g., formic or acetic acid), making it ideal for orthogonal protection strategies in complex peptide sequences without affecting other functional groups. The diethylammonium salt form improves solubility in polar organic solvents, aiding handling and purification in solid-phase or solution-phase synthesis. Commonly used in producing pharmaceutical intermediates and bioactive peptides requiring high purity and stereochemical integrity.
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