N-((1R, 4R)-4-(3-Chloro-4-cyanophenoxy)cyclohexyl)-6-(4-((4-(2-(2, 6-dioxopiperidin-3-yl)-6-fluoro-1, 3-dioxo-2, 3-dihydro-1H-isoindol-5-yl)piperazin-1-yl)methyl)piperidin-1-yl)pyridazine-3-carboxamide

10mM in DMSO

Reagent Code: #216277
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CAS Number 2222112-77-6

science Other reagents with same CAS 2222112-77-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 812.29 g/mol
Formula C₄₁H₄₃ClFN₉O₆
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in pharmaceutical research as a targeted protein degrader, specifically functioning as a heterobifunctional PROTAC (proteolysis-targeting chimera). It is designed to selectively recruit specific disease-related proteins to an E3 ubiquitin ligase, inducing ubiquitination and subsequent degradation by the cell's proteasome system. This compound shows potential in oncology research due to its ability to modulate hard-to-target proteins involved in cancer progression. Its structure enables enhanced cell permeability and target specificity, making it valuable in developing therapies for resistant or undruggable targets.

Available Sizes & Pricing

Size Availability Unit Price Quantity
1ml
10-20 days ฿4,200.00
N-((1R, 4R)-4-(3-Chloro-4-cyanophenoxy)cyclohexyl)-6-(4-((4-(2-(2, 6-dioxopiperidin-3-yl)-6-fluoro-1, 3-dioxo-2, 3-dihydro-1H-isoindol-5-yl)piperazin-1-yl)methyl)piperidin-1-yl)pyridazine-3-carboxamide
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Used in pharmaceutical research as a targeted protein degrader, specifically functioning as a heterobifunctional PROTAC (proteolysis-targeting chimera). It is designed to selectively recruit specific disease-related proteins to an E3 ubiquitin ligase, inducing ubiquitination and subsequent degradation by the cell's proteasome system. This compound shows potential in oncology research due to its ability to modulate hard-to-target proteins involved in cancer progression. Its structure enables enhanced cell permeability and target specificity, making it valuable in developing therapies for resistant or undruggable targets.
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