4-nitrophenyl 2-(pyridin-2-yldisulfanyl)ethyl carbonate
10mM in DMSO
Reagent
Code: #216388
CAS Number
874302-76-8
science Other reagents with same CAS 874302-76-8
blur_circular Chemical Specifications
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Molecular Information
Weight
352.39 g/mol
Formula
C₁₄H₁₂N₂O₅S₂
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Registry Numbers
MDL Number
MFCD28556879
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Storage & Handling
Storage
-20°C
description Product Description
Used in the synthesis of antibody-drug conjugates (ADCs) as a linker component, enabling controlled release of cytotoxic agents in targeted cancer therapies. Its disulfide bond provides redox sensitivity, allowing drug release in the reducing environment of cancer cells. Also employed in bioconjugation techniques for labeling proteins and antibodies due to its selective reactivity with thiol groups. Suitable for constructing prodrugs and functionalized polymers in pharmaceutical research.
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