NVP-LAQ824
10mM in DMSO
Reagent
Code: #216470
CAS Number
404951-53-7
science Other reagents with same CAS 404951-53-7
blur_circular Chemical Specifications
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Molecular Information
Weight
379.459 g/mol
Formula
C₂₂H₂₅N₃O₃
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Registry Numbers
MDL Number
MFCD09970778
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Storage & Handling
Storage
-20°C
description Product Description
Used in research for its potent inhibition of histone deacetylases (HDACs), particularly HDAC1, HDAC2, and HDAC3. This activity leads to increased histone acetylation, resulting in altered gene expression that can induce cell cycle arrest, differentiation, and apoptosis in cancer cells. It has shown antitumor effects in preclinical models of leukemia, breast cancer, and other solid tumors. Due to its ability to modulate chromatin structure and affect oncogenic pathways, it is investigated as a potential therapeutic agent in epigenetic cancer therapy. Also used as a tool compound in studies exploring HDAC inhibition mechanisms and combination therapies with other anticancer agents.
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