Used as a chiral ligand in asymmetric catalysis, particularly in enantioselective transformations such as Diels-Alder reactions and conjugate additions. Its rigid cyclohexane backbone with defined stereochemistry enhances stereoselectivity. Commonly coordinates with metal centers like copper(II) or nickel(II) to form complexes that promote high enantiomeric excess in product formation. Applied in pharmaceutical synthesis where control of stereochemistry is critical. Also investigated in sensor design for chiral recognition of small molecules.