N-Acetyl-2-(4-fluoro-phenyl)-D-glycine
95%
science Other reagents with same CAS 136814-99-8
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description Product Description
Used in pharmaceutical synthesis as a chiral building block and intermediate for developing bioactive molecules, particularly in the production of beta-lactam antibiotics such as semi-synthetic penicillins (e.g., ampicillin analogs) and cephalosporins, as well as protease inhibitors and anti-inflammatory agents. Its fluorinated aromatic structure enhances metabolic stability, binding affinity, cell permeability, and overall molecular stability in drug candidates. Commonly employed in research settings for structure-activity relationship (SAR) studies due to its stereochemical purity and functional group compatibility. Also utilized in the development of peptide mimetics where enhanced lipophilicity and electronic effects are required. The N-acetyl protection group facilitates selective reactions in multi-step syntheses.
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