N-(2-(1H-1,2,4-Triazol-1-yl)-5-(trifluoromethoxy)phenyl)-4-(cyclopropylmethoxy)-3-methoxybenzamide

98%

Reagent Code: #219423
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CAS Number 2313526-86-0

science Other reagents with same CAS 2313526-86-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 448.402 g/mol
Formula C₂₁H₁₉F₃N₄O₄
inventory_2 Storage & Handling
Storage Room temperature, inert gas

description Product Description

Used as a potent antifungal agent, particularly effective against a broad spectrum of fungal pathogens including Aspergillus and Candida species. It functions by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes, through the blockade of lanosterol 14α-demethylase (CYP51). This disruption leads to increased membrane permeability and fungal cell death. The compound exhibits strong tissue penetration and prolonged half-life, making it suitable for systemic treatment of invasive fungal infections. It is primarily developed for intravenous or oral administration in clinical settings for immunocompromised patients, such as those undergoing chemotherapy or organ transplantation. Its trifluoromethoxy and triazole groups enhance metabolic stability and antifungal potency, while the cyclopropylmethoxy moiety contributes to improved pharmacokinetic properties.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿11,690.00
inventory 50mg
10-20 days ฿19,860.00
inventory 100mg
10-20 days ฿33,750.00
N-(2-(1H-1,2,4-Triazol-1-yl)-5-(trifluoromethoxy)phenyl)-4-(cyclopropylmethoxy)-3-methoxybenzamide
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Used as a potent antifungal agent, particularly effective against a broad spectrum of fungal pathogens including Aspergillus and Candida species. It functions by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes, through the blockade of lanosterol 14α-demethylase (CYP51). This disruption leads to increased membrane permeability and fungal cell death. The compound exhibits strong tissue penetration and prolonged half-life, making it suitable for systemic treatment of in

Used as a potent antifungal agent, particularly effective against a broad spectrum of fungal pathogens including Aspergillus and Candida species. It functions by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes, through the blockade of lanosterol 14α-demethylase (CYP51). This disruption leads to increased membrane permeability and fungal cell death. The compound exhibits strong tissue penetration and prolonged half-life, making it suitable for systemic treatment of invasive fungal infections. It is primarily developed for intravenous or oral administration in clinical settings for immunocompromised patients, such as those undergoing chemotherapy or organ transplantation. Its trifluoromethoxy and triazole groups enhance metabolic stability and antifungal potency, while the cyclopropylmethoxy moiety contributes to improved pharmacokinetic properties.

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