N-Me-Phe-Obzl p-Tosylate
97%
science Other reagents with same CAS 40298-25-7
blur_circular Chemical Specifications
description Product Description
N-Me-Phe-Obzl p-Tosylate is a salt form of N-methyl-phenylalanine benzyl ester, serving as a key building block in peptide synthesis. The benzyl ester protects the C-terminal carboxylic acid, enabling selective deprotection under mild hydrogenation conditions, while the N-methyl substitution on the amino group provides steric and electronic modifications that influence peptide folding and receptor interactions. The p-tosylate counterion improves solubility in organic solvents and stabilizes the protonated amino group during storage and coupling steps, preventing unwanted side reactions. Widely used in pharmaceutical and biochemical research for synthesizing complex bioactive peptides, including hormone analogs, enzyme inhibitors, and antimicrobial agents. Compatible with both solid-phase and solution-phase methodologies.
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