N-(1,4-Dioxo-3-(Pyrazin-2-Ylmethylamino)-1,4-Dihydronaphthalen-2-Yl)-N-(2-Methoxyethyl)Acetamide
98%
science Other reagents with same CAS 355405-02-6
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description Product Description
Used as a key intermediate in the synthesis of protein degraders, particularly in PROTAC (Proteolysis Targeting Chimeras) technology. It functions as a linker component that connects the target protein binder to an E3 ubiquitin ligase recruiter, enabling selective degradation of disease-related proteins. Its structure supports stability and proper spatial orientation between the two functional moieties, enhancing degradation efficiency. Commonly applied in research for developing anticancer and neurodegenerative disease therapeutics. Also utilized in biochemical assays to study protein-protein interactions and cellular signaling pathways due to its ability to induce targeted protein degradation.
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