5-bromo-N-methyl-1H-pyrazolo[3,4-b]pyridin-3-amine
97%
science Other reagents with same CAS 1289189-96-3
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description Product Description
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in pharmaceutical research targeting cancer therapies. It plays a role in the development of selective inhibitors for protein kinases such as PIM kinases and FLT3, which are involved in cell signaling pathways associated with tumor growth and survival. Its structure enables effective binding to ATP sites in kinases, making it valuable in designing small molecule drugs for hematological malignancies and other cancers. Also employed in medicinal chemistry for structure-activity relationship (SAR) studies to optimize potency and selectivity of drug candidates.
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