N-(4-butylphenyl)-2-[(3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio]acetamide

≥90%

Reagent Code: #220733
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CAS Number 1040632-67-4

science Other reagents with same CAS 1040632-67-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 463.62 g/mol
Formula C₂₅H₂₅N₃O₂S₂
badge Registry Numbers
MDL Number MFCD11997067
inventory_2 Storage & Handling
Storage 2-8°C, sealed, dry, light-proof

description Product Description

Used in research as a potent and selective inhibitor of Janus kinase 3 (JAK3), this compound plays a role in studying immune-mediated diseases. It helps modulate cytokine signaling pathways involved in inflammation and autoimmunity, making it valuable in the development of therapies for conditions like rheumatoid arthritis, psoriasis, and transplant rejection. Due to its selectivity for JAK3 over other JAK family members, it provides a tool for minimizing off-target effects in cellular and preclinical studies. Its structure supports high binding affinity to the JAK3 ATP-binding site, enhancing its utility in pharmacological assays and structure-activity relationship (SAR) studies.

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Size Availability Unit Price Quantity
inventory 1mg
10-20 days ฿5,990.00
N-(4-butylphenyl)-2-[(3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio]acetamide
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Used in research as a potent and selective inhibitor of Janus kinase 3 (JAK3), this compound plays a role in studying immune-mediated diseases. It helps modulate cytokine signaling pathways involved in inflammation and autoimmunity, making it valuable in the development of therapies for conditions like rheumatoid arthritis, psoriasis, and transplant rejection. Due to its selectivity for JAK3 over other JAK family members, it provides a tool for minimizing off-target effects in cellular and preclinical st

Used in research as a potent and selective inhibitor of Janus kinase 3 (JAK3), this compound plays a role in studying immune-mediated diseases. It helps modulate cytokine signaling pathways involved in inflammation and autoimmunity, making it valuable in the development of therapies for conditions like rheumatoid arthritis, psoriasis, and transplant rejection. Due to its selectivity for JAK3 over other JAK family members, it provides a tool for minimizing off-target effects in cellular and preclinical studies. Its structure supports high binding affinity to the JAK3 ATP-binding site, enhancing its utility in pharmacological assays and structure-activity relationship (SAR) studies.

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