N-(4-butylphenyl)-2-[(3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio]acetamide
≥90%
science Other reagents with same CAS 1040632-67-4
blur_circular Chemical Specifications
description Product Description
Used in research as a potent and selective inhibitor of Janus kinase 3 (JAK3), this compound plays a role in studying immune-mediated diseases. It helps modulate cytokine signaling pathways involved in inflammation and autoimmunity, making it valuable in the development of therapies for conditions like rheumatoid arthritis, psoriasis, and transplant rejection. Due to its selectivity for JAK3 over other JAK family members, it provides a tool for minimizing off-target effects in cellular and preclinical studies. Its structure supports high binding affinity to the JAK3 ATP-binding site, enhancing its utility in pharmacological assays and structure-activity relationship (SAR) studies.