N-(Tert-butoxycarbonyl)-3,3,3-trifluoroalanine
98%
Reagent
Code: #220854
CAS Number
188030-43-5
science Other reagents with same CAS 188030-43-5
blur_circular Chemical Specifications
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Molecular Information
Weight
243.18 g/mol
Formula
C₈H₁₂F₃NO₄
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Registry Numbers
MDL Number
MFCD10697680
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Physical Properties
Boiling Point
303.8±42.0 °C(Predicted)
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Storage & Handling
Density
1.319±0.06 g/cm3(Predicted)
Storage
2-8°C, Sealed
description Product Description
Widely used in peptide synthesis as a protected amino acid building block. The tert-butoxycarbonyl (Boc) group provides acid-labile protection for the amine functionality, allowing selective deprotection under mild acidic conditions without affecting other sensitive groups in complex peptide chains. The presence of trifluoromethyl group enhances metabolic stability and lipophilicity, making this derivative valuable in the development of pharmaceuticals, particularly in medicinal chemistry for designing protease inhibitors and bioactive peptides with improved pharmacokinetic properties. Commonly employed in solid-phase and solution-phase synthesis for constructing fluorinated peptides used in drug discovery and biochemical research.
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