N-(Tert-butoxycarbonyl)-3,3,3-trifluoroalanine

98%

Reagent Code: #220854
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CAS Number 188030-43-5

science Other reagents with same CAS 188030-43-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 243.18 g/mol
Formula C₈H₁₂F₃NO₄
badge Registry Numbers
MDL Number MFCD10697680
thermostat Physical Properties
Boiling Point 303.8±42.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.319±0.06 g/cm3(Predicted)
Storage 2-8°C, Sealed

description Product Description

Widely used in peptide synthesis as a protected amino acid building block. The tert-butoxycarbonyl (Boc) group provides acid-labile protection for the amine functionality, allowing selective deprotection under mild acidic conditions without affecting other sensitive groups in complex peptide chains. The presence of trifluoromethyl group enhances metabolic stability and lipophilicity, making this derivative valuable in the development of pharmaceuticals, particularly in medicinal chemistry for designing protease inhibitors and bioactive peptides with improved pharmacokinetic properties. Commonly employed in solid-phase and solution-phase synthesis for constructing fluorinated peptides used in drug discovery and biochemical research.

Available Sizes & Pricing

Size Availability Unit Price Quantity
100mg
10-20 days ฿26,720.00
250mg
10-20 days ฿37,910.00
N-(Tert-butoxycarbonyl)-3,3,3-trifluoroalanine
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Widely used in peptide synthesis as a protected amino acid building block. The tert-butoxycarbonyl (Boc) group provides acid-labile protection for the amine functionality, allowing selective deprotection under mild acidic conditions without affecting other sensitive groups in complex peptide chains. The presence of trifluoromethyl group enhances metabolic stability and lipophilicity, making this derivative valuable in the development of pharmaceuticals, particularly in medicinal chemistry for designing protease inhibitors and bioactive peptides with improved pharmacokinetic properties. Commonly employed in solid-phase and solution-phase synthesis for constructing fluorinated peptides used in drug discovery and biochemical research.
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