3-(1-oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione hydrochloride

95%

Reagent Code: #221047
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CAS Number 2222120-31-0

science Other reagents with same CAS 2222120-31-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 364.8266 g/mol
Formula C₁₇H₂₁ClN₄O₃
badge Registry Numbers
MDL Number MFCD32705051
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer therapy and immune modulation. The compound's piperazine and piperidine dione moieties enhance solubility and binding affinity, supporting optimization of drug candidates with improved pharmacokinetic profiles.

Available Sizes & Pricing

Size Availability Unit Price Quantity
100mg
10-20 days ฿3,200.00
250mg
10-20 days ฿4,800.00
1g
10-20 days ฿12,800.00
3-(1-oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione hydrochloride
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Used in pharmaceutical research as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing PROTACs (proteolysis-targeting chimeras) for cancer therapy and immune modulation. The compound's piperazine and piperidine dione moieties enhance solubility and binding affinity, supporting optimization of drug candidates with improved pharmacokinetic profiles.
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