Used primarily in veterinary medicine, especially for dogs, to manage pruritus (itching) associated with allergic dermatitis. It works by modulating the immune response, specifically targeting Janus kinases (JAK) involved in inflammation and itch signaling. Commonly prescribed for atopic dermatitis, it provides rapid relief from itching, often within 24 hours of administration. Also used off-label for other inflammatory skin conditions in pets. Its selective action allows for effective symptom control with fewer systemic side effects compared to traditional steroids.