5´-O-(4,4´-Dimethoxytrityl)-thymidine-3´-O-succinic acid

95%

Reagent Code: #222236
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CAS Number 74405-40-6

science Other reagents with same CAS 74405-40-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 644.668 g/mol
Formula C₃₅H₃₆N₂O₁₀
inventory_2 Storage & Handling
Storage Room temperature, seal, dry

description Product Description

Widely used in oligonucleotide synthesis, particularly in the production of DNA probes and primers. Acts as a key building block for solid-phase synthesis, where the dimethoxytrityl group provides reversible protection for the 5'-hydroxyl, enabling stepwise chain elongation. The succinic acid linker at the 3' position allows for efficient attachment to solid supports such as controlled pore glass or polystyrene beads. This compound is essential in the manufacture of custom DNA sequences used in PCR, gene synthesis, and diagnostic applications. Its protected functional groups ensure high coupling efficiency and purity during automated synthesis cycles.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿12,240.00
inventory 5g
10-20 days ฿41,380.00
5´-O-(4,4´-Dimethoxytrityl)-thymidine-3´-O-succinic acid
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Widely used in oligonucleotide synthesis, particularly in the production of DNA probes and primers. Acts as a key building block for solid-phase synthesis, where the dimethoxytrityl group provides reversible protection for the 5'-hydroxyl, enabling stepwise chain elongation. The succinic acid linker at the 3' position allows for efficient attachment to solid supports such as controlled pore glass or polystyrene beads. This compound is essential in the manufacture of custom DNA sequences used in PCR, gene synthesis, and diagnostic applications. Its protected functional groups ensure high coupling efficiency and purity during automated synthesis cycles.
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