5´-O-(4,4´-Dimethoxytrityl)-thymidine-3´-O-succinic acid
95%
Reagent
Code: #222236
CAS Number
74405-40-6
science Other reagents with same CAS 74405-40-6
blur_circular Chemical Specifications
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Molecular Information
Weight
644.668 g/mol
Formula
C₃₅H₃₆N₂O₁₀
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Widely used in oligonucleotide synthesis, particularly in the production of DNA probes and primers. Acts as a key building block for solid-phase synthesis, where the dimethoxytrityl group provides reversible protection for the 5'-hydroxyl, enabling stepwise chain elongation. The succinic acid linker at the 3' position allows for efficient attachment to solid supports such as controlled pore glass or polystyrene beads. This compound is essential in the manufacture of custom DNA sequences used in PCR, gene synthesis, and diagnostic applications. Its protected functional groups ensure high coupling efficiency and purity during automated synthesis cycles.