Used to treat pruritus (itching) in patients with progressive familial intrahepatic cholestasis (PFIC), a rare liver disease. It works by inhibiting the ileal bile acid transporter, reducing bile acid accumulation in the liver and bloodstream, which helps improve liver function and relieve symptoms. Taken orally, it targets the root cause of cholestasis rather than just managing symptoms, offering a targeted therapy for pediatric patients with this genetic disorder.