Used as an intermediate in organic synthesis, particularly in the preparation of phosphorylated compounds and modified biomolecules. It reacts selectively with hydroxyl and amino groups, making it valuable in the development of prodrugs and nucleotide analogs. Commonly employed in the synthesis of phosphoramidate derivatives for antiviral and anticancer research. Its reactivity allows for the introduction of phosphate-mimicking groups in peptide and carbohydrate chemistry, enhancing metabolic stability and bioavailability of target molecules.