Used as a highly effective scale and corrosion inhibitor in water treatment systems, particularly in cooling towers and boilers. It prevents the formation of calcium carbonate, calcium sulfate, and other mineral deposits by chelating metal ions such as calcium, magnesium, and iron, and dispersing scale-forming particles. Offers excellent stability in the presence of chlorine and other oxidizing agents, making it suitable for chlorinated environments, and maintains stability at high pH levels.

Commonly used in industrial water treatment, reverse osmosis systems, and detergents to enhance performance, soften water, and extend equipment life. Also employed in cleaning formulations for metal surface treatment due to its ability to remove rust and oxide layers while protecting the underlying metal. In the oil and gas industry, it controls scaling in pipes and equipment exposed to high-mineral groundwater.

With partial biodegradability and low environmental toxicity, HEDP·Kx is a preferred alternative to phosphate-based inhibitors in applications requiring greater environmental friendliness.