Panobinostat
10mM in DMSO
Reagent
Code: #224095
CAS Number
404950-80-7
science Other reagents with same CAS 404950-80-7
blur_circular Chemical Specifications
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Molecular Information
Weight
349.43 g/mol
Formula
C₂₁H₂₃N₃O₂
thermostat
Physical Properties
Melting Point
114-117 °C
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in the treatment of multiple myeloma, a type of blood cancer. It works by inhibiting histone deacetylases (HDACs), which helps control the growth and survival of cancer cells. Often prescribed in combination with other drugs like bortezomib and dexamethasone for patients who have already undergone several lines of therapy. Its mechanism promotes cancer cell death by allowing increased expression of tumor-suppressing genes. Also being studied in clinical trials for other cancers, including lymphomas and solid tumors, due to its ability to alter gene expression and disrupt protein balance in malignant cells.
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