PD406976

10mM in DMSO

Reagent Code: #224104
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CAS Number 136194-77-9

science Other reagents with same CAS 136194-77-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 377.42 g/mol
Formula C₂₄H₁₈N₄O
badge Registry Numbers
MDL Number MFCD00236434
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in research as a selective inhibitor of protein kinase C (PKC) isoforms, particularly PKCβ. It is employed in cellular signaling studies to investigate the role of PKC in processes such as cell proliferation, differentiation, and apoptosis. Commonly applied in cancer research to assess the impact of PKC inhibition on tumor growth and survival pathways. Also utilized in studies related to diabetic complications, where PKCβ activation is implicated in vascular and retinal dysfunction. Its selectivity makes it a valuable tool for dissecting specific PKC-mediated signaling events without broad off-target effects on other kinase families.

Available Sizes & Pricing

Size Availability Unit Price Quantity
1ml
10-20 days ฿6,180.00
PD406976
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Used in research as a selective inhibitor of protein kinase C (PKC) isoforms, particularly PKCβ. It is employed in cellular signaling studies to investigate the role of PKC in processes such as cell proliferation, differentiation, and apoptosis. Commonly applied in cancer research to assess the impact of PKC inhibition on tumor growth and survival pathways. Also utilized in studies related to diabetic complications, where PKCβ activation is implicated in vascular and retinal dysfunction. Its selectivity makes it a valuable tool for dissecting specific PKC-mediated signaling events without broad off-target effects on other kinase families.
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