1-Propynylmagnesium bromide
0.4 M solution in THF, MkSeal
Reagent
Code: #224364
CAS Number
16466-97-0
science Other reagents with same CAS 16466-97-0
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Molecular Information
Weight
143.26 g/mol
Formula
C₃H₃BrMg
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used as a strong nucleophile in organic synthesis, particularly for carbon-carbon bond formation. It reacts with carbonyl compounds such as aldehydes, ketones, and esters to introduce a propynyl group, enabling the synthesis of propargylic alcohols. These intermediates are valuable in the preparation of complex molecules including pharmaceuticals, agrochemicals, and natural products. Also employed in reactions with epoxides and nitriles to extend carbon chains. Its reactivity makes it useful in research settings for constructing alkyne-containing structures important in materials science and medicinal chemistry.
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