Used as an activating agent in organic synthesis, particularly in peptide coupling reactions, where it helps form amide bonds by converting carboxylic acids into reactive intermediates. It is also employed in the preparation of carbamates and other ester derivatives. Due to its ability to introduce propoxycarbonyl groups, it serves in protecting group strategies for amines in multistep syntheses. Commonly used in pharmaceutical and agrochemical manufacturing for building complex molecules. Requires careful handling due to its lachrymatory and moisture-sensitive properties.