1-PYRROLIDINECARBONYL CHLORIDE

95%

Reagent Code: #225132
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CAS Number 1192-63-8

science Other reagents with same CAS 1192-63-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 133.58 g/mol
Formula C₅H₈ClNO
badge Registry Numbers
MDL Number MFCD00051321
thermostat Physical Properties
Boiling Point 104-106℃ 14mm Hg (Lit.)
inventory_2 Storage & Handling
Storage -20℃

description Product Description

Used as an acylating agent in organic synthesis, particularly in the preparation of amides and esters. It reacts with amines to form N-acylpyrrolidine derivatives, which are useful intermediates in pharmaceutical manufacturing. Commonly employed in the synthesis of active pharmaceutical ingredients (APIs) due to its ability to introduce the pyrrolidine carbonyl moiety, enhancing metabolic stability and bioavailability in drug molecules. Also utilized in peptide chemistry for protection and coupling steps. Sensitive to moisture, so reactions are typically carried out under anhydrous conditions.

Available Sizes & Pricing

Size Availability Unit Price Quantity
1g
10-20 days ฿680.00
25g
10-20 days ฿13,700.00
5g
10-20 days ฿2,980.00
1-PYRROLIDINECARBONYL CHLORIDE
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Used as an acylating agent in organic synthesis, particularly in the preparation of amides and esters. It reacts with amines to form N-acylpyrrolidine derivatives, which are useful intermediates in pharmaceutical manufacturing. Commonly employed in the synthesis of active pharmaceutical ingredients (APIs) due to its ability to introduce the pyrrolidine carbonyl moiety, enhancing metabolic stability and bioavailability in drug molecules. Also utilized in peptide chemistry for protection and coupling steps

Used as an acylating agent in organic synthesis, particularly in the preparation of amides and esters. It reacts with amines to form N-acylpyrrolidine derivatives, which are useful intermediates in pharmaceutical manufacturing. Commonly employed in the synthesis of active pharmaceutical ingredients (APIs) due to its ability to introduce the pyrrolidine carbonyl moiety, enhancing metabolic stability and bioavailability in drug molecules. Also utilized in peptide chemistry for protection and coupling steps. Sensitive to moisture, so reactions are typically carried out under anhydrous conditions.

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