Phyllostine is primarily used in research settings for its potential neuroprotective properties. It has shown activity in modulating neuronal signaling pathways, making it a compound of interest in the study of neurodegenerative diseases such as Alzheimer's and Parkinson's. Its ability to cross the blood-brain barrier enhances its utility in central nervous system studies. Additionally, phyllostine exhibits anti-inflammatory effects in neural tissues, which may contribute to its protective role in brain injury models. It is also employed as a biochemical tool to probe serotonin receptor interactions due to structural similarities with known monoaminergic ligands. Ongoing studies explore its potential in developing novel therapeutics for cognitive and mood disorders.