Used in pharmaceutical research as a key intermediate in the synthesis of kinase inhibitors, particularly targeting cancer-related proteins such as ALK (anaplastic lymphoma kinase) and ROS1. Its structure enables strong binding to ATP sites in these enzymes, making it valuable in developing targeted therapies for non-small cell lung cancer and other malignancies. Also explored in the design of compounds with potential neuroprotective and anti-inflammatory activity. Commonly modified to improve selectivity, bioavailability, and blood-brain barrier penetration in drug candidates.