Phenyl((trimethylsilyl)ethynyl)iodonium trifluoromethanesulfonate
97%
science Other reagents with same CAS 133816-00-9
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description Product Description
Used as a highly efficient hypervalent iodine reagent in organic synthesis, particularly for alkyne transfer reactions. It enables mild and selective ethynylation of various nucleophiles, including enolates, heteroatom nucleophiles, and electron-rich aromatics. Its trimethylsilyl-protected alkyne group allows for easy deprotection to terminal alkynes, making it valuable in the synthesis of conjugated enynes, natural products, and functional materials. The reagent is especially useful in palladium- or copper-catalyzed cross-coupling reactions, offering high yields with minimal byproducts. Its stability and reactivity profile make it suitable for late-stage functionalization in pharmaceutical and agrochemical research.
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