Phenyl((trimethylsilyl)ethynyl)iodonium trifluoromethanesulfonate

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Reagent Code: #227858
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CAS Number 133816-00-9

science Other reagents with same CAS 133816-00-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 450.29 g/mol
Formula C₁₂H₁₄F₃IO₃SSi
inventory_2 Storage & Handling
Storage -20°C, Sealed, Dry, Lightproof, Inert Gas

description Product Description

Used as a highly efficient hypervalent iodine reagent in organic synthesis, particularly for alkyne transfer reactions. It enables mild and selective ethynylation of various nucleophiles, including enolates, heteroatom nucleophiles, and electron-rich aromatics. Its trimethylsilyl-protected alkyne group allows for easy deprotection to terminal alkynes, making it valuable in the synthesis of conjugated enynes, natural products, and functional materials. The reagent is especially useful in palladium- or copper-catalyzed cross-coupling reactions, offering high yields with minimal byproducts. Its stability and reactivity profile make it suitable for late-stage functionalization in pharmaceutical and agrochemical research.

Available Sizes & Pricing

Size Availability Unit Price Quantity
250mg
10-20 days ฿2,930.00
1g
10-20 days ฿8,300.00
5g
10-20 days ฿33,890.00
Phenyl((trimethylsilyl)ethynyl)iodonium trifluoromethanesulfonate
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Used as a highly efficient hypervalent iodine reagent in organic synthesis, particularly for alkyne transfer reactions. It enables mild and selective ethynylation of various nucleophiles, including enolates, heteroatom nucleophiles, and electron-rich aromatics. Its trimethylsilyl-protected alkyne group allows for easy deprotection to terminal alkynes, making it valuable in the synthesis of conjugated enynes, natural products, and functional materials. The reagent is especially useful in palladium- or cop

Used as a highly efficient hypervalent iodine reagent in organic synthesis, particularly for alkyne transfer reactions. It enables mild and selective ethynylation of various nucleophiles, including enolates, heteroatom nucleophiles, and electron-rich aromatics. Its trimethylsilyl-protected alkyne group allows for easy deprotection to terminal alkynes, making it valuable in the synthesis of conjugated enynes, natural products, and functional materials. The reagent is especially useful in palladium- or copper-catalyzed cross-coupling reactions, offering high yields with minimal byproducts. Its stability and reactivity profile make it suitable for late-stage functionalization in pharmaceutical and agrochemical research.

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