Used in bioconjugation processes to link proteins, peptides, or other biomolecules to surfaces or carriers through amine group coupling. Commonly applied in immobilizing antibodies or antigens on biosensor chips, microplates, or nanoparticles for diagnostic assays. Enables controlled orientation of biomolecules, improving binding efficiency and signal detection in immunoassays. Also utilized in crosslinking studies to capture transient protein-protein interactions in cellular systems. Stable in aqueous buffers at physiological pH, making it suitable for labeling biomolecules without disrupting their native structure. Frequently used in preparing functionalized polymers for drug delivery systems where targeted release is required.