(R,E)-2-Methyl-N-(2,2,2-trifluoroethylidene)propane-2-sulfinamide
97%
Reagent
Code: #228583
CAS Number
1219607-83-6
science Other reagents with same CAS 1219607-83-6
blur_circular Chemical Specifications
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Molecular Information
Weight
201.2095 g/mol
Formula
C₆H₁₀NOF₃S
thermostat
Physical Properties
Boiling Point
189.3±50.0 °C(Predicted)
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Storage & Handling
Density
1.25±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as a chiral auxiliary in asymmetric synthesis, particularly in the preparation of enantiomerically pure amines and amino acids. Its structure enables efficient stereocontrol during carbon–carbon and carbon–heteroatom bond-forming reactions. Commonly employed in sulfinyl imine chemistry, it reacts with nucleophiles such as organometallic reagents to deliver high diastereoselectivity. After serving its role, the auxiliary can be cleaved under mild acidic conditions, leaving the desired chiral amine intact. Widely applied in pharmaceutical synthesis where stereochemistry is critical for biological activity.