(R)-1-(3-Chlorophenyl)-2,2,2-trifluoroethanamine
95%
Reagent
Code: #228607
CAS Number
1213627-66-7
science Other reagents with same CAS 1213627-66-7
blur_circular Chemical Specifications
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Molecular Information
Weight
209.5982 g/mol
Formula
C₈H₇ClF₃N
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Registry Numbers
MDL Number
MFCD07374615
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Physical Properties
Boiling Point
228.4±40.0 °C(Predicted)
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Storage & Handling
Density
1.352±0.06 g/cm3(Predicted)
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Used as a chiral building block in the synthesis of pharmaceuticals, particularly in the development of central nervous system agents. Its trifluoromethyl group enhances metabolic stability and lipophilicity, making it valuable in drug design for improving bioavailability and binding affinity. Commonly employed in the preparation of serotonin and norepinephrine reuptake inhibitors, where the (R)-enantiomer shows higher biological activity. Also utilized in agrochemicals for creating bioactive molecules with improved environmental stability.