rel-(R,R)-Voriconazole is a triazole antifungal agent used to treat serious fungal infections, including aspergillosis, candidemia, and other invasive candidiasis in adults and children. It is effective against a broad range of fungi, particularly invasive species such as Aspergillus spp. and Candida spp., especially when other antifungal therapies are not suitable or have failed.

Commonly administered intravenously or orally in hospital and outpatient settings, it is particularly valuable for immunocompromised patients such as those with cancer undergoing chemotherapy, organ transplants, or HIV with complicating fungal infections.

Its high bioavailability and ability to penetrate tissues, including the central nervous system, make it suitable for treating severe or disseminated infections.

Due to numerous potential drug interactions, caution is advised when used with other medications, and therapeutic drug monitoring may be required in some cases to prevent adverse effects, such as neurological symptoms or liver dysfunction.