N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)-benzenesulfonamidehydrochloride

97%

Reagent Code: #229187
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CAS Number 187397-18-8

science Other reagents with same CAS 187397-18-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 649.08 g/mol
Formula C₂₇H₃₂ClF₃N₄O₇S
inventory_2 Storage & Handling
Storage -20°C, Sealed, Dry

description Product Description

Used in pharmaceutical research as a potent and selective inhibitor of histone deacetylase (HDAC), particularly HDAC6. This compound shows promise in the development of treatments for cancer due to its ability to induce apoptosis and inhibit tumor cell proliferation. It is also investigated for its potential in neurodegenerative diseases, where modulation of HDAC activity may help restore normal cellular function. Its sulfonamide and trifluoromethyl groups enhance membrane permeability and metabolic stability, making it suitable for in vivo studies. Commonly employed in preclinical assays to evaluate HDAC-targeted therapies.

Available Sizes & Pricing

Size Availability Unit Price Quantity
10mg
10-20 days ฿9,170.00
25mg
10-20 days ฿18,340.00
100mg
10-20 days ฿50,970.00
N-[5-[5-(2,4-Dioxo-1,3,8-triazaspiro[4.5]dec-8-yl)-1-oxopentyl]-2,4-dimethoxyphenyl]-4-(trifluoromethyl)-benzenesulfonamidehydrochloride
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Used in pharmaceutical research as a potent and selective inhibitor of histone deacetylase (HDAC), particularly HDAC6. This compound shows promise in the development of treatments for cancer due to its ability to induce apoptosis and inhibit tumor cell proliferation. It is also investigated for its potential in neurodegenerative diseases, where modulation of HDAC activity may help restore normal cellular function. Its sulfonamide and trifluoromethyl groups enhance membrane permeability and metabolic stab

Used in pharmaceutical research as a potent and selective inhibitor of histone deacetylase (HDAC), particularly HDAC6. This compound shows promise in the development of treatments for cancer due to its ability to induce apoptosis and inhibit tumor cell proliferation. It is also investigated for its potential in neurodegenerative diseases, where modulation of HDAC activity may help restore normal cellular function. Its sulfonamide and trifluoromethyl groups enhance membrane permeability and metabolic stability, making it suitable for in vivo studies. Commonly employed in preclinical assays to evaluate HDAC-targeted therapies.

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