Calcium (3R,5S,Z)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate

95%

Reagent Code: #229265
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CAS Number 1159588-21-2

science Other reagents with same CAS 1159588-21-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 880.98 g/mol
Formula C₅₀H₄₆CaF₂N₂O₈
inventory_2 Storage & Handling
Storage 2-8°C, Sealed, Inert Gas

description Product Description

Widely used in the pharmaceutical industry as an active ingredient in cholesterol-lowering medications, particularly for managing hyperlipidemia and reducing the risk of cardiovascular diseases. It functions by inhibiting HMG-CoA reductase, a key enzyme in cholesterol synthesis, leading to decreased levels of low-density lipoprotein (LDL) cholesterol in the bloodstream. Its stereochemistry enhances metabolic stability and target specificity, improving therapeutic efficacy. Commonly prescribed for long-term management of patients with a history of heart disease or stroke, it also helps stabilize atherosclerotic plaques and reduce systemic inflammation markers. Due to its calcium salt form, it offers improved crystalline stability and formulation consistency in oral dosage forms.

Available Sizes & Pricing

Size Availability Unit Price Quantity
1mg
10-20 days ฿7,200.00
5mg
10-20 days ฿21,580.00
25mg
10-20 days ฿73,290.00
100mg
10-20 days ฿211,750.00
Calcium (3R,5S,Z)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate
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Widely used in the pharmaceutical industry as an active ingredient in cholesterol-lowering medications, particularly for managing hyperlipidemia and reducing the risk of cardiovascular diseases. It functions by inhibiting HMG-CoA reductase, a key enzyme in cholesterol synthesis, leading to decreased levels of low-density lipoprotein (LDL) cholesterol in the bloodstream. Its stereochemistry enhances metabolic stability and target specificity, improving therapeutic efficacy. Commonly prescribed for long-term management of patients with a history of heart disease or stroke, it also helps stabilize atherosclerotic plaques and reduce systemic inflammation markers. Due to its calcium salt form, it offers improved crystalline stability and formulation consistency in oral dosage forms.
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