Calcium (3R,5S,Z)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate
95%
Reagent
Code: #229265
CAS Number
1159588-21-2
science Other reagents with same CAS 1159588-21-2
blur_circular Chemical Specifications
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Molecular Information
Weight
880.98 g/mol
Formula
C₅₀H₄₆CaF₂N₂O₈
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Storage & Handling
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Widely used in the pharmaceutical industry as an active ingredient in cholesterol-lowering medications, particularly for managing hyperlipidemia and reducing the risk of cardiovascular diseases. It functions by inhibiting HMG-CoA reductase, a key enzyme in cholesterol synthesis, leading to decreased levels of low-density lipoprotein (LDL) cholesterol in the bloodstream. Its stereochemistry enhances metabolic stability and target specificity, improving therapeutic efficacy. Commonly prescribed for long-term management of patients with a history of heart disease or stroke, it also helps stabilize atherosclerotic plaques and reduce systemic inflammation markers. Due to its calcium salt form, it offers improved crystalline stability and formulation consistency in oral dosage forms.
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