(1R,2S)-1-Amino-1-(4-fluorophenyl)propan-2-ol hydrochloride
95%(HPLC)
Reagent
Code: #229331
CAS Number
2828440-04-4
science Other reagents with same CAS 2828440-04-4
blur_circular Chemical Specifications
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Molecular Information
Weight
205.66 g/mol
Formula
C₉H₁₃ClFNO
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Storage & Handling
Storage
Room temperature, seal, inert gas
description Product Description
Used as a key chiral intermediate in the synthesis of selective serotonin reuptake inhibitors (SSRIs), particularly in the production of antidepressant medications. Its stereochemistry allows for high enantioselectivity in drug synthesis, improving the efficacy and reducing side effects of the final pharmaceutical product. Commonly employed in asymmetric synthesis routes due to its stable amine-alcohol functionality, which readily participates in reductive amination and nucleophilic addition reactions. Also utilized in the preparation of biologically active molecules where fluorinated aromatic moieties enhance metabolic stability and membrane permeability.
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