(3aR,7aR)-1,3-Dimesityl-3a,4,5,6,7,7a-hexahydro-1H-benzo[d]imidazol-3-ium tetrafluoroborate
98%
Reagent
Code: #229401
CAS Number
372517-05-0
science Other reagents with same CAS 372517-05-0
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Molecular Information
Weight
448.35 g/mol
Formula
C₂₅H₃₃BF₄N₂
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
This chiral imidazolium salt serves as a precatalyst or ligand precursor in transition metal-catalyzed reactions, particularly enabling asymmetric catalysis in palladium-catalyzed cross-coupling reactions such as Suzuki, Heck, and Negishi couplings for stereoselective carbon-carbon bond formation in pharmaceutical and agrochemical synthesis. Its rigid bicyclic structure with defined (3aR,7aR) stereochemistry enhances catalytic efficiency, stability, and enantioselectivity under various conditions. The tetrafluoroborate counterion improves solubility in polar organic solvents, supporting homogeneous catalysis. Additionally, it is utilized in asymmetric olefin metathesis within N-heterocyclic carbene (NHC) frameworks, providing high activity and selectivity for ring-closing and ring-opening metathesis in complex molecule synthesis. It is preferred in industrial processes requiring long catalyst lifetimes, low loadings, and high stereocontrol.
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