3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine

10mM in DMSO

Reagent Code: #229706
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CAS Number 877399-52-5

science Other reagents with same CAS 877399-52-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 450.34 g/mol
Formula C₂₁H₂₂Cl₂FN₅O
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used in the treatment of autoimmune diseases such as psoriasis and rheumatoid arthritis. It functions as a selective inhibitor of Janus kinase (JAK), particularly JAK1, which plays a key role in the signaling pathways of various cytokines involved in inflammation. By modulating the JAK-STAT pathway, it helps reduce immune system overactivity and inflammation. Currently under investigation in clinical trials for its efficacy and safety in chronic inflammatory conditions. Shows potential for oral administration with targeted action, offering advantages over biologic therapies.

Available Sizes & Pricing

Size Availability Unit Price Quantity
1ml
10-20 days ฿3,750.00
3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine
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Used in the treatment of autoimmune diseases such as psoriasis and rheumatoid arthritis. It functions as a selective inhibitor of Janus kinase (JAK), particularly JAK1, which plays a key role in the signaling pathways of various cytokines involved in inflammation. By modulating the JAK-STAT pathway, it helps reduce immune system overactivity and inflammation. Currently under investigation in clinical trials for its efficacy and safety in chronic inflammatory conditions. Shows potential for oral administration with targeted action, offering advantages over biologic therapies.
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