3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine
10mM in DMSO
Reagent
Code: #229706
CAS Number
877399-52-5
science Other reagents with same CAS 877399-52-5
blur_circular Chemical Specifications
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Molecular Information
Weight
450.34 g/mol
Formula
C₂₁H₂₂Cl₂FN₅O
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Storage & Handling
Storage
-20°C
description Product Description
Used in the treatment of autoimmune diseases such as psoriasis and rheumatoid arthritis. It functions as a selective inhibitor of Janus kinase (JAK), particularly JAK1, which plays a key role in the signaling pathways of various cytokines involved in inflammation. By modulating the JAK-STAT pathway, it helps reduce immune system overactivity and inflammation. Currently under investigation in clinical trials for its efficacy and safety in chronic inflammatory conditions. Shows potential for oral administration with targeted action, offering advantages over biologic therapies.
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