Used primarily as a muscle relaxant to treat spasticity associated with multiple sclerosis and spinal cord injuries. It acts on the central nervous system, specifically targeting GABA-B receptors to reduce excessive muscle tone and involuntary muscle contractions. Also investigated for use in managing chronic pain and certain types of epilepsy. Additionally, (R)-baclofen has been studied for its potential in reducing alcohol and cocaine dependence due to its effect on neurotransmitter release in reward pathways of the brain.