Roflumilast

99%

Reagent Code: #229944
label
Alias 3-(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridyl)-4-(difluoromethoxy)benzamide
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CAS Number 162401-32-3
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Properties DMSO: soluble20 mg/mL, clear

science Other reagents with same CAS 162401-32-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 403.21 g/mol
Formula C₁₇H₁₄Cl₂F₂N₂O₃
thermostat Physical Properties
Melting Point 158°C
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used primarily in the treatment of severe chronic obstructive pulmonary disease (COPD), this compound helps reduce airway inflammation and prevent disease exacerbations. It acts as a selective inhibitor of phosphodiesterase-4, which increases cyclic AMP levels in inflammatory cells, leading to decreased release of pro-inflammatory mediators. It is particularly beneficial in patients with chronic bronchitis and a history of frequent flare-ups. The compound is administered orally and has shown efficacy in improving lung function and health-related quality of life. It may also have potential in treating other inflammatory conditions such as asthma, psoriasis, and atopic dermatitis, though these uses are less established.

Available Sizes & Pricing

Size Availability Unit Price Quantity
500mg
10-20 days ฿960.00
1g
10-20 days ฿1,520.00
25g
10-20 days ฿22,590.00
5g
10-20 days ฿5,050.00
Roflumilast
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Used primarily in the treatment of severe chronic obstructive pulmonary disease (COPD), this compound helps reduce airway inflammation and prevent disease exacerbations. It acts as a selective inhibitor of phosphodiesterase-4, which increases cyclic AMP levels in inflammatory cells, leading to decreased release of pro-inflammatory mediators. It is particularly beneficial in patients with chronic bronchitis and a history of frequent flare-ups. The compound is administered orally and has shown efficacy in

Used primarily in the treatment of severe chronic obstructive pulmonary disease (COPD), this compound helps reduce airway inflammation and prevent disease exacerbations. It acts as a selective inhibitor of phosphodiesterase-4, which increases cyclic AMP levels in inflammatory cells, leading to decreased release of pro-inflammatory mediators. It is particularly beneficial in patients with chronic bronchitis and a history of frequent flare-ups. The compound is administered orally and has shown efficacy in improving lung function and health-related quality of life. It may also have potential in treating other inflammatory conditions such as asthma, psoriasis, and atopic dermatitis, though these uses are less established.

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