(R)-2-(piperidin-3-yl)isoindoline-1,3-dione

98%

Reagent Code: #229979
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CAS Number 886588-61-0

science Other reagents with same CAS 886588-61-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 266.72 g/mol
Formula C₁₃H₁₅ClN₂O₂
badge Registry Numbers
MDL Number MFCD09752972
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of targeted protein degraders such as PROTACs (proteolysis-targeting chimeras). Its structural features allow for effective linker attachment between an E3 ligase ligand and a target protein binder. Commonly employed in oncology research due to its ability to engage cereblon (CRBN), an E3 ubiquitin ligase, facilitating the degradation of disease-causing proteins. Also utilized in the design of small molecule therapeutics for immunomodulatory and anti-inflammatory applications. Its chiral piperidine core supports high selectivity and binding affinity in complex biological systems.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿6,800.00
inventory 25g
10-20 days ฿55,800.00
inventory 5g
10-20 days ฿18,600.00
(R)-2-(piperidin-3-yl)isoindoline-1,3-dione
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Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of targeted protein degraders such as PROTACs (proteolysis-targeting chimeras). Its structural features allow for effective linker attachment between an E3 ligase ligand and a target protein binder. Commonly employed in oncology research due to its ability to engage cereblon (CRBN), an E3 ubiquitin ligase, facilitating the degradation of disease-causing proteins. Also utilized in the design of small mole

Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of targeted protein degraders such as PROTACs (proteolysis-targeting chimeras). Its structural features allow for effective linker attachment between an E3 ligase ligand and a target protein binder. Commonly employed in oncology research due to its ability to engage cereblon (CRBN), an E3 ubiquitin ligase, facilitating the degradation of disease-causing proteins. Also utilized in the design of small molecule therapeutics for immunomodulatory and anti-inflammatory applications. Its chiral piperidine core supports high selectivity and binding affinity in complex biological systems.

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