Reactive Red 195 is primarily used in the textile industry for dyeing cellulosic fibers such as cotton, rayon, and linen. It is especially effective in dyeing under alkaline conditions, where it forms strong covalent bonds with the fiber, resulting in excellent color fastness to washing and light exposure. This dye is commonly applied in batch processes like exhaust and pad-batch methods, offering uniform dyeing and good reproducibility.

It is also used in the printing of textiles, providing bright red shades with good clarity. Due to its reactive nature, it shows high fixation rates, which reduces dye wastage and lowers the environmental impact of effluent treatment. Reactive Red 195 is suitable for cold pad-batch dyeing, making it energy-efficient compared to high-temperature processes.

Additionally, it finds application in the dyeing of paper and leather, where vibrant red tones and durability are required. Its solubility in water and reactivity under mild alkaline conditions make it a preferred choice in sustainable textile processing.