Rupestonic acid is primarily used in dermatological formulations for its anti-inflammatory and skin-conditioning properties. It helps in reducing redness and irritation, making it suitable for sensitive or acne-prone skin. Due to its ability to modulate skin cell activity, it is often included in anti-aging products to support skin texture and tone. Additionally, rupestonic acid exhibits mild antimicrobial effects, enhancing its role in treatments aimed at preventing bacterial growth on the skin. Its stability in various pH ranges allows for broad formulation compatibility in creams, serums, and lotions.