(R)-2-(Tert-Butoxycarbonyl)-5-(Methylsulfonyl)Isoindoline-1-Carboxylic Acid

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Reagent Code: #231645
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CAS Number 2101238-70-2

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blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 341.38 g/mol
Formula C₁₅H₁₉NO₆S
inventory_2 Storage & Handling
Storage Room temperature

description Product Description

Used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of proteolysis-targeting chimeras (PROTACs). Its structural features allow for efficient conjugation to E3 ligase ligands, enabling targeted protein degradation. The methylsulfonyl group enhances binding selectivity, while the Boc-protected amine facilitates further functionalization. Commonly employed in medicinal chemistry for optimizing linker regions in bifunctional molecules, contributing to improved pharmacokinetic properties and degradation efficiency of target proteins.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿30,680.00
(R)-2-(Tert-Butoxycarbonyl)-5-(Methylsulfonyl)Isoindoline-1-Carboxylic Acid
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Used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of proteolysis-targeting chimeras (PROTACs). Its structural features allow for efficient conjugation to E3 ligase ligands, enabling targeted protein degradation. The methylsulfonyl group enhances binding selectivity, while the Boc-protected amine facilitates further functionalization. Commonly employed in medicinal chemistry for optimizing linker regions in bifunctional molecules, contributing to

Used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of proteolysis-targeting chimeras (PROTACs). Its structural features allow for efficient conjugation to E3 ligase ligands, enabling targeted protein degradation. The methylsulfonyl group enhances binding selectivity, while the Boc-protected amine facilitates further functionalization. Commonly employed in medicinal chemistry for optimizing linker regions in bifunctional molecules, contributing to improved pharmacokinetic properties and degradation efficiency of target proteins.

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