(R)-2-(Tert-Butoxycarbonyl)-5-(Methylsulfonyl)Isoindoline-1-Carboxylic Acid
97%
science Other reagents with same CAS 2101238-70-2
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description Product Description
Used as a key chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of proteolysis-targeting chimeras (PROTACs). Its structural features allow for efficient conjugation to E3 ligase ligands, enabling targeted protein degradation. The methylsulfonyl group enhances binding selectivity, while the Boc-protected amine facilitates further functionalization. Commonly employed in medicinal chemistry for optimizing linker regions in bifunctional molecules, contributing to improved pharmacokinetic properties and degradation efficiency of target proteins.
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